Roselle flowers – RMIT University
An unassuming plant and the antioxidants it contains, could be a legitimate health food weight loss supplement, after a landmark trial found it decreased fat absorption.
When human fat cells were treated with polyphenols contained in the flower, they inhabited the production of the chief enzyme that converts dietary fat into stored fat in our cells.
One of the co-authors, a food scientist and former farmer from Nepal, believes that it could replace many of the side-effect-inducing pharmaceutical substances taken to genesis fat loss in the Australian public.
There’s nothing wrong with A: trying to find a food-based alternative to synthetic medications, and B: trying to use health foods as a way to aid in weight loss.
Roselle flower (Hibiscus Sabdariffa), dried and brewed in teas, is a common sight in traditional Chinese medicine shops, which offer a long legacy of other proven plant medications such as reishi mushroom.
From cinnamon to fennel seed, there are all kinds of plant materials touted for having health benefits, but often the funding just isn’t there for dedicated scientific research to prove such claims either way.
Fortunately, Ph.D. candidate Manisha Singh was able to do just that.
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She treated human stem cells with the polyphenolic compounds in roselle flowers, which stains it and everything it touches red, before turning them into fat cells called adipocytes. Most cells can become fat cells—all they have to do is receive a biological command to absorb fats, usually through the diet.
The fat cells treated with the polyphenols absorbed 95% fewer fats than the non-treated ones.
Fat droplets (before and after) – RMIT University
“The phenolic extracts from the roselle could help create a health food product that is effective in interfering with the formation of fat cells, but also bypass the bad side effects of some medications,” said Singh’s Ph.D. supervisor Professor Benu Adhikari at Royal Melbourne Institute of Technology.
Singh had previously found that roselle extracts contained some of the chemicals present in weight loss medication like Orlistat and Liraglutide. She discovered it inhibited the function of lipase, an enzyme used in the body to break large dietary fats down into smaller ones to be absorbed in the cells.
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By inhibiting the lipase enzyme, the fat cannot be absorbed and is passed through the colon as waste.
Roselle isn’t difficult to cultivate in bulk, and powdered into a capsule form, could create the ultimate aid to a healthy diet and exercise for weight loss, since it was only observed stopping fats from entering the cells, and had no effect on fat already inside the cells.
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